화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔)
권호 12권 1호, p.415
발표분야 생물화공
제목 Optimization of Process Variables for High Cell Concentration of Saccharomyces cerevisiae JUL3 in Fed-Batch Cultures
초록 The β-glucan is one of the most abundant polysaccharides in the yeast cell wall. It shows a variety of biological activities (immunoadjuvants, antitumor, radioprotective agents, etc.). The primary use of β-glucan isolated from the cell wall of yeast is to enhance the immune system. Saccharomyces cerevisiae JUL3 producing highly branched β-glucan was developed through UV mutagenesis and laminarinase resistance. Optimization of molasses and corn steep liquor was performed by using response surface methodology (RSM) for the production of β-glucan by S. cerevisiae JUL3. In this study, we tested process variables such as aeration and agitation, feeding rate in a 2.5L stirred tank reactor (STR) for the production of high cell concentration of yeast.
Acknowledgement : This work is supporting by Biogreen 21 (200504010347981870300) through the Rural Development Administration.
저자 김영환1, 강성우1, 장효일1, 윤철원1, 백현동2, 강창원2, 김승욱1
소속 1고려대, 2건국대
키워드 Saccharomyces cerevisiae JUL3; β-glucan; Response surface methodology (RSM); Stirred tank reactor (STR)
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