| 초록 |
Polydimethylsiloxane (PDMS) is a material that has a wide range of application for micro, nanotechnology, and biological research field. However, PDMS has a unique property that tends to adsorb organic compounds and biomolecules such as proteins, DNA, etc. Here, we optimized a method of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxdie) (PEO-PPO-PEO) block copolymer embedding, for solving non-specific protein and biomolecular adsorption and high hydrophobicic surface property. PEO is a material having an ability to prevent the surface from non-specific adsorption when having above certain molecular weight. We assessed its surface modification by controlling the concentration of embedded block copolymer, water-soaking time, and recovery time as variables by contact angle measurements. Furthermore, we generated oil-in-water (O/W) emulsion as a proof-of-concept experiment to confirm that the optimized surface modification works properly. |
