화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2021년 봄 (04/07 ~ 04/09, 대전컨벤션센터)
권호 46권 1호
발표분야 분자전자 부문위원회 Ⅱ
제목 Supramolecular peptide hydrogel-based 3D-electrical network for brain signal sensing and cell proliferation
초록 Recording neural activity from the brain is of great interest in neuroscience for interpreting cognitive processing. Despite recent advances in neural technologies, development of a soft neural interface that integrates with neural tissues, increases recording sensitivity, and prevents signal dissipation remains a major challenge. In this talk, I introduce a biocompatible and conductive neural interface that allows unprecedented signal amplification via tight neural/hydrogel contact without neuroinflammation. The non-biodegradable β- peptide forms a multi-hierarchical structure with conductive nanomaterial, creating a three-dimensional electrical network. By achieving seamless integration in brain tissue with increased contact area and tight neural tissue coupling, the intercortical and epidural neural signals recorded with the hydrogel were augmented. Overall, our tissue-like chronic neural interface will facilitate a deeper understanding of brain oscillation in broad brain states
저자 김용호
소속 성균관대
키워드 protein design; conducting hydrogel; brain signal
E-Mail