| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Water-Soluble Perylenediimide Derivatives for Biological Fluorescence Imaging |
| 초록 |
we report the synthesis of the water soluble perylenediimide derivative (J1-PDI) and the investigation of in vitro and in vivo bioimaging and biomedical characteristics. Perylenediimide derivatives have been shown highly fluorescent labels for biologically probes. However, their poor solubility has limited the application in the bioimaging and biosensing. To improve their solubility, perylenediimide was coupled with poly(ethylene glycol) (PEG), which endowed the good water solubility and biocompatibility to the fluorescent. Compared to the in vivo bioimaging of the control without PEG, the one of the PEG derivatized J1-PDI demonstrated the superb fluorescent imaging. Also, we confirmed it is applicable to in vivo or cellular imaging. |
| 저자 |
박진경1, 김란희1, 박진순1, 김세훈2, 이광섭1
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| 소속 |
1한남대, 2한국과학기술(연) |
| 키워드 |
Water-Soluble Perylenediimide Derivatives; Fluorescence Imaging
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| E-Mail |
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