| 학회 |
한국화학공학회 |
| 학술대회 |
2008년 봄 (04/23 ~ 04/25, 제주ICC) |
| 권호 |
14권 1호, p.1210 |
| 발표분야 |
재료 |
| 제목 |
Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer |
| 초록 |
Novel multifunctional magneto-polymeric nanohybrids (MMPNs) were synthesized using ultra sensitive MnFe2O4 nanocrystals as MR contrast agents, chemotherapeutic agents, and encapsulating amphiphilic block copolymer for targeted detection via MRI and synergistic therapeutic effects on breast cancer. The MMPNs demonstrated ultrasensitive targeted detection in MR images of in vitro and in vivo models. Furthermore, the HER-modified MMPNs showed excellent synergistic effects for inducing breast cancer cell death. |
| 저자 |
양재문1, 이충환2, 고현주1, 서진석1, 허용민1, 함승주1
|
| 소속 |
1연세대, 2ATGen |
| 키워드 |
multifunctional; magnetic; nanohybrids; cancer; diagnosis; treatment
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
