| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
기능성고분자－막분리용 고분자 |
| 제목 |
Synthesis of Poly(ethylene oxide -b- maleic acid) and its modification using folate. |
| 초록 |
Poly(ethylene oxide) based block copolymers have received a great attention in biological field due to its bio-compatibility and water solubility. The N-phenyl maleimide group has been well known to be readily deimidated for a long time. In this respect, we have successfully synthesized poly(ethylene oxide)-block-poly(N-phenyl maleimide) copolymer via anionic living polymerization. Anionic ring-opening polymerization of ethylene oxide using n-butyl lithium and potassium t-butoxide as initiator was at first performed in the mixture of THF/benzene/ DMSO, followed by polymerization of N-phenylmaleimide. The resulting THF-soluble product was deimidated in DMSO at 120° for 24 hour using hydrazine monohydrate leading to the production of PEO-b-PMAc. The resulting product was reacted with folic acid in presence of DCC/NHS in DMF. In this presentation we will show the preliminary results. |
| 저자 |
시디크 아부 바카, 조영준, 남주현, 최우석, 권난현, 이재혁, 강호정, 이재열, 김정안
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| 소속 |
경희대 |
| 키워드 |
Poly(ethylene oxide -b- maleic acid); block copolymer; poly(ethylene oxide)-block-poly(N-phenyl maleimide)
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| E-Mail |
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