| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Photocrosslinkable Thermoresponsive Star Polymers for Control of Cell-Surface Interactions |
| 초록 |
Star polymers with thermoresponsive arms, consisting of 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) and oligo(ethylene glycol) methacrylate with ~ 4 ethylene oxide units (OEOMA300, Mn = 300), were synthesized via atom transfer radical polymerization (ATRP). A fraction of the arms contained benzophenone chainend functionality at the star periphery. A mixture of linear (benzophenone)-poly(MEO2MA-co-OEOMA300) macroinitiator (Bzp-MI) and poly(MEO2MA-co-OEOMA300) macroinitiator (MI) were incorporated into a central core by chain extending the MI with ethylene glycol dimethacrylate. The UV-vis spectroscopy revealed that the star polymers exhibit the low critical solution temperature (LCST) at 26.5oC. A polystyrene substrate was modified by photocrosslinking a deposited film with the dual functional stars, under UV irradiation. The star polymers covalently attached onto surfaces allowed a precise control of the interaction between the surfaces and the cells through temperature changes. |
| 저자 |
박상우1, 백현종1, Krzysztof Matyjaszewski2
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| 소속 |
1부산대, 2Carnegie Mellon Univ. |
| 키워드 |
Thermoresponsiveness; Photocrosslinking; Cell Adhesion; Surface Modification; Atom Transfer Radical Polymerization |
| E-Mail |
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