| 초록 |
This study proposed and examined the potential use and merits of microfluidic sensors for the direct analysis of cell response, biofilm formation and eradication of P. aeruginosa PAO1 using a new synthetic chemical, 1-TDPPO, which has organic compounds of prop-2-en-1-one and difluoro phenyl. The combination of two organic compounds exhibits a stronger antimicrobial efficacy than the more commonly used antibacterial agents. Using a microfluidic sensor embedded in microstructures and synthetic 1-TDPPO, the biofilm was eradicated in a short time and exhibited outstanding antimicrobial efficacy. 20% and 90% ethanol solutions led to successful performances of eradicating biofilm formation, but sufficient mixing time should be considered in advance. |
