화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2019년 가을 (10/23 ~ 10/25, 대전컨벤션센터)
권호 25권 2호, p.1503
발표분야 생물화공 (Biochemical Engineering)
제목 Establishment of Cell-MOF hybrid system  
초록 Mammalian cells are protected by a membrane. However, cellular membrane is fragile and easy to break by external mechanical stresses. Exterior coating (synthetic coating) can protect the living cells from external stress coming from the environment. While the synthetic coating on living cells can afford persistent cellular viability to environmental stress, it should also allow the exchange of nutrients and stimulants necessary for cell survival. Metal-Organic frameworks (MOF) is known as porous coordination polymers that has exceptional chemical robust ness and thermal stability. Due to its high thermal and chemical stabilities, recently, the integration of MOF with biomolecules has risen as a promising way to protect the biofunctionality of biological substances. Here, we reports a simple synthesis method of coating MOF on living mammalian cells.
저자 하미진, 김동표, 강동창
소속 포항공과대
키워드 생물화학공학
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