| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
나노_포스터 |
| 제목 |
Manufacture of HA nanofibrous webs and drug release characteristics |
| 초록 |
HA (hyaluronic acid) is a natural biopolymer with complete biocompatibility, moisturizing, anti-aging, and drug delivery characteristics. It is a compound with repeated structure of D-glucuronic acid and N-acetylglucosamine. Such HA can be used in medical and cosmetic fields if it is made into nanofibrous webs by electrospinning. However, since HA has a property of forming a large molecular aggregate and forming a gel by binding with water, it is difficult to produce HA nanofibrous webs. In order to solve these problems, we have succeeded in manufacturing nanofibrous webs by adding PVA, PVP, and BA (boric acid) to HA, and confirmed the morphology using FE-SEM. In addition, drug release experiments were conducted for medical and cosmetic applications, and excellent drug release performance was confirmed with UV-Vis. The crosslinking and physical properties of the nanofibers were confirmed by GPC, FT-IR, TGA and UTM. |
| 저자 |
박병준1, 허훈1, 김희진1, 오성근2, 소대섭3, 이영우4
|
| 소속 |
1한국생산기술(연), 2한양대, 3한국과학기술정보(연), 4헵틸와이 |
| 키워드 |
HA; nanofibrous web; crosslinking; drug release
|
| E-Mail |
|
