| 학회 |
한국화학공학회 |
| 학술대회 |
2001년 가을 (10/19 ~ 10/20, 한밭대학교) |
| 권호 |
7권 2호, p.3931 |
| 발표분야 |
생물화공 |
| 제목 |
재조합 효모의 유가식 배양을 통한 외래 단백질 생산의 최적화 |
| 초록 |
In the recombinant plasmid systems, cell mass maximization doesn't necessarily guarantee the maximization of protein production. Moreover, in GAL system, the manipulated variables are glucose feeding rate and galactose feeding rate. Optimization of bioreactors with two control variables is considered very difficult and there have been few attempts. The dynamics of fed-batch fermentation in recombinant yeast will be analyzed in terms of galactose uptake rate, induction time of galactose, and the effect of glucose and ethanol. The adaptive optimization strategy developed will be applied to this expression system. |
| 저자 |
나정걸1, 김현한2, 장용근3, 정봉현
|
| 소속 |
1(주)에스티알바이오텍 중앙(연), 2한국과학기술원 화학공학과, 3생명공학(연) |
| 키워드 |
recombinant yeast; fed-batch; hPTH
|
| E-Mail |
, |
| VOD |
VOD 보기 |
| 원문파일 |
초록 보기 |
