화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터)
권호 16권 2호
발표분야 포스터-정보.전자소재
제목 Poly(allyl methacrylate) Functionalized Hydroxyapatite Nanocrystals via the Combination of Surface-Initiated RAFT Polymerization and Thiol-Ene Protocol: A Potential Anticancer Drug Nanocarrier
초록 Hydroxyapatite nanocrystals (HAP NCs) were encapsulated by poly(allyl methacrylate) (PolyAMA) employing controlled surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of allyl methacrylate to afford HAP-PolyAMA nanohybrids. The nanohybrids were investigated by FT-IR , XPS, EDS, TGA, FE-SEM. Employing thiol-ene chemistry, HAP-Poly(AMA-COOH) was prepared for nanocarrier. Anticancer agent cisplatin was incorporated into HAP-Poly(AMA-COOH). In vitro examination of the nanomedicine showed their potentialities against cancer cells.
저자 임권택, Long Giang Bach, Md. Rafiqul Islam, 장명재
소속 부경대
키워드 Anticancer Drug Nanocarrier
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