| 초록 |
Nanogels have drawn much attention as one of the promising materials in developing drug delivery system. Owing to superior water swelling property, nanogels are prefered to load large amounts of molecules including biomolecules, growth factors, and drugs. Herein, we easily synthesize the light-responsive nanogels composed of plasmonic nanoparticles and thermo-sensitive molecules. We tune the physicochemical properties of hybrid nanogels in terms of size and composition. Then, we observe controlled releases of the loaded molecules via light-induced local heating such as photothermal-conversion effect of the embedded plasmonic nanoparticles. Furthermore, we achieve the successful light-induced molecular delivery into the live cells. We envision that the proposed light-responsive hybrid nanogels would be beneficial materials in developing new drug delivery method. |
