화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2003년 가을 (10/24 ~ 10/25, 한양대학교)
권호 9권 2호, p.1946
발표분야 분리기술
제목 Simultaneous Determination of Isotherm Parameters and Diffusivity for Cephalosporin C in μ-Bondapak C18 Chromatography
초록 From a practical point of view, an ideal method for the simultaneous determination of adsorption equilibrium and mass transfer parameters has been required for the separation and purification of chemical and biochemicals(amino acids, antibiotics and proteins) from dilute mixtures in order to design a chromatography separation process. In this work, we examine the accuracy of isotherm parameters and a mass transfer coefficients within the adsorbernt which were estimated from an analysis of HPLC chromatograms and from batch experiments. The procedure involves matching the shape of experimental HPLC chromatogram with that predicted from a simplified set of model equations for a pulse of adsorbate propagating through ! a μ-Bondapak C18 HPLC column. Here, an orthogonal collocation on finite elements method was used to solve the model equations.
저자 조대림1, 심왕근1, 이재욱2, 문 희1
소속 1전남대, 2서남대
키워드 Chromatography; Cephalosporin C; Adsorption Equilibrium; Mass Transfer Coefficient
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