| 학회 | 한국공업화학회 |
| 학술대회 | 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 | 25권 1호 |
| 발표분야 | 포스터-생체재료 |
| 제목 | Augmented Mechanical and Biological Characteristics of PLLA Composites through Surface-modified Magnesium Hydroxide with Oligo(lactide-co-caprolactone) |
| 초록 | The most commonly used biodegradable polymer in biomedical material is poly (L-lactic acid) (PLLA). However, it has some drawbacks such as low hydrophilicity, slow degradation and acidic degradation product. In addition, the in vivo degraded acidic by-products can lead to noninfectious inflammatory response in the body. Incorporation of magnesium hydroxide (MH) into PLLA can improve the mechanical properties and inflammation suppression by pH neutralizing effect during hydrolytic degradation. In this study, we prepared the PLLA composite containing surface-modified MH with oligo(lactide-co-caprolactone) (OLCL) to improve the mechanical and biological characteristics of the organic–inorganic hybrid composite. It is suggested that the modified MH can provide an effective means to develop optimized biomaterials including stents. |
| 저자 | 송덕현, 백승운, 허윤, 한동근 |
| 소속 | 차의과학대 |
| 키워드 | PLLA; Magnesium Hydroxide; Oligo(lactide-co-caprolactone) |
