| 학회 | 한국재료학회 |
| 학술대회 | 2014년 가을 (11/27 ~ 11/28, 대전컨벤션센터) |
| 권호 | 20권 2호 |
| 발표분야 | D. 바이오 재료(Biomaterials) |
| 제목 | Bone Tissue Engineering and Drug Delivery |
| 초록 | In recent years, injectable hydrogels have attracted more and more attention in the field of biomedical applications because of their easy administration, the minimally invasive procedures associated with their site specific introduction and patient convenience. In particular, injectable hydrogels are extensively studied because of their ability to form three-dimensional networks under mild conditions. They are attractive carriers for drug delivery, especially for proteins and cells. The development of recombinant DNA technology has made it possible for the commercial production of bioactive peptides to be used in biomedical application. But, the bioactive peptides are normally expensive and fragile. The delivery of the peptides is carried out mainly by compatible and biodegradable vehicles in order to avoid functional loss and to gain long-term therapeutic effect of the factors. Stem cells based therapies have generated significant interest and are regarded as the future of various medical procedures and treatments. In order to improve the mechanical properties of scaffolds for bone tissue engineering, the study aims to bring calcium carbonate with signaling molecules, namely pearl powder, into poly(L-lactic acid). REFERENCES [1] RW Tan, ZD She, MB Wang, X Yu, H Jin, JY Li, QL Feng. Journal of Tissue Engineering and Regenerative Medicine. 6(8), 614-621(2012). [2] MB Wang, QL Feng, ZD She, RW Tan, XF Niu. Polymer Degradation and Stability. 96(1), 107-113, (2011). [3] Z Huang, B Yu, QL Feng, SJ Li, Y Chen, LQ Luo. Carbohydrate Polymers 85(1), 261-267, (2011). [4] YS Liu，QL Huang, QL Feng, NM Hu. Journal of Mechanics in Medicine and Biology, 13(1), 20-35, (2013). |
| 저자 | Qingling Feng |
| 소속 | Tsinghua Univ. |
| 키워드 | Injectable hydrogel; Scaffold; Controlled release; Stem cells; Pearl |
