화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2006년 가을 (10/27 ~ 10/28, 고려대학교)
권호 12권 2호, p.1631
발표분야 분리기술
제목 SMB Simulation by Aspen Chromatography for Mandelic Acid Separation
초록 Simulated moving bed (SMB) chromatography is a suitable process for continuous separation of chiral compounds. We have designed our own lab-scale SMB chromatography using 5 HPLC pumps as well as 4 stainless steel columns to separate a racemic mixture of mandelic acid. Operating parameters(flow rates of four zones, switching time and feed concentration and so on) for SMB chromatography have been calculated from batch chromatography experiments and the triangle theory. we performed simulations with Aspen Chromatography which is a powerful tool of chromatographic simulation.

Acknowledgement
It is supported by BSEP ERC of Inha university as well as KOSEF grant number R01-2005-000-10245-0
저자 이 은, 김인호
소속 충남대
키워드 Mandelic acid; Aspen chromatography; SMB chromatography
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