| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Remotely Controlled Drug Release via Centripetal Rotation Using Adjustable Magnetic Chains |
| 초록 |
Remotely controlled drug release has been recognized as one of the most promising research areas for biomedical applications. In this study, we use a superparamagnetic property without spontaneous magnetization and aggregated form, remotely controlled rotation towards its own magnetic direction can generate magnetic torque. This property has not yet been used to drug release systems because of technical difficulties to synthesize mesoporous superparamagnetic nanorods (MSPN). We compared cell death depends on the length of MSPN at the same magnetic strength, periodic magnetic field and loaded doxorubicin amount. Consequently, the longest MSPN triggers cell death easily, and these results demonstrate that we can control dose amount of drug by controlling length of MSPN. |
| 저자 |
강병훈, 장은지, 한승민, 신무광, 김현욱, 서진석, 허용민, 함승주
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| 소속 |
연세대 |
| 키워드 |
Controlled Drug Release; Magnetic Chains; Centripetal Rotation
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| E-Mail |
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