화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2014년 가을 (10/22 ~ 10/24, 대전 DCC)
권호 20권 2호, p.1194
발표분야 고분자
제목 Poly (N-isopropyl acrylamide-co-Acrylic acid) graft Polyaspartamide Coated Magnetic Nanoparticles for Hyperthermia and Chemotherapy
초록 A series of pH- and thermo-sensitive poly(N-isopropyl acrylamide-co-acrylic acid) were synthesized by radical polymerization and grafted on polysuccinimide backbones. The polysuccinimide derivatives synthesized were coated on thermal-decomposition iron oxide magnetic nanoparticles for potential applications in drug delivery systems with hyperthermia and chemotherapy. The structure of polymer-shell and iron oxide was confirmed by FT-IR and 1H-NMR spectroscopies and TEM. The particle size and its behaviors distribution is measured by ELS measurement and TEM. The thermal behaviors of coated materials were tested by applying the high frequency magnetic field by hyperthermia system.
저자 TRAN THI THUY VAN, 김덕준
소속 성균관대
키워드 PNIPAM-co-PAA; hyperthermia; pH-sensitive; iron oxide; core-shell
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