초록 |
Methane is a predominant component of natural gas, shale gas, and biogas. Accordingly, the interest in the utilization of methane via biochemical processes using methanotropic bacteria has increased, because they require less energy than chemical processes. In this study, we converted methane to methanol in fed-batch and continuous bioreactors using methanotropic bacteria as a biocatalyst. In order to obtain higher productivity and titer, appropriate inhibitors of methanol dehydrogenase and reducing power source were supplied. As a result, we could successfully convert methane to methanol in reactor-scale with high volumetric productivity. The results suggest the potential of methanotropic bacteria for the commercialization of industrial methanol production from methane. |