| 초록 |
Recently, methanotrophs have attracted much attention as a biocatalyst for the production of various chemicals from methane. Generally, the productivity of wild-type methanotrophs as the catalyst is low. Thus, improvement of their catalytic activity is required and strain improvement through metabolic engineering can be considered as a promising solution. Genomic and transcriptomic analysis of the strain is prerequisite to analyze metabolic engineering targets. Genome of Methylomonas sp. DH-1, a newly isolated methanotroph strain from beer brewery plant waste, was sequenced using Illumina seq and PacBio, and then genomic data were assembled and annotated. RNA seq was conducted to analyze transcriptional profiles for Methylomonas sp. DH-1 cultured on methane and methanol as the sole carbon source to characterize the metabolic ability of C1 assimilation and secondary metabolite biosynthesis. |
