| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Fabrication of Biodegradable Polyurethane Scaffolds with Controlled Porous Structures for Tissue Engineering |
| 초록 |
In this study, we have fabricated the biodegradable poly(ester-urethane)urea (PEUU) foams with porous structure for articular cartilage tissue engineering. The PEUU foams were synthesized from hexamethylene diisocyanate (HMDI) and polycaprolactone triol (PCL). Putrescine and dimethyl sulfoxide (DMSO) were used as chain extender and solvent, respectively. To improve the pore interconnectivity of PEUU foams, we used water-in-oil emulsification method by sonicator. The morphology of PEUU foams was characterized by scanning electron microscopy (SEM). The chemical structure and molecular characteristics of PEUU foams was analyzed by nuclear magnetic resonance spectroscopy (NMR). Degradation test of PEUU foams was performed in phosphate buffered saline at 37℃. These biodegradable and flexible PEUU foams demonstrate potential for future application as cell scaffolds in other soft tissue applications. |
| 저자 |
최성욱, 이지선
|
| 소속 |
가톨릭대 |
| 키워드 |
Polyurethane; Scaffold; Biodegradation
|
| E-Mail |
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