화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 생체재료_포스터
제목 Drug Release from Visible-Light Curable Hyaluronic Acid Derivative Gel for Tendon Anti-adhesion
초록 Visible-light curable hyaluronic acid derivative (furfuryl hyaluronic acid, F-HA) was prepared to reduce adhesion of inter-tissue after surgical operation. If unexpected adhesion is happened after surgical treatment, re-operation is needed because of reserve pains and inflammation reactions to patient. Hyaluronic acid has biocompatibility, wound-healing effect, and biodegradable properties. In this study, We expect that F-HA could prevent adhesion because F-HA could make physical separation by coating the surgical surface. Structure of prepared F-HA was analyzed using 1H-NMR. Also, for medical application, biocompatibility of F-HA was evaluated by WST assay. From these results, F-HA could be developed as biocompatible anti-adhesion.
Acknowledgements
This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and future Planning (No. NRF-2014R1A2A1A11052623)
저자 한가득, 김은혜, 정진홍, 노승현, 김재원, 이재관, 손태일
소속 중앙대
키워드 Hyaluronic acid; Photo-curable; Anti-adhesion; Drug delivery system
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