| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Anti-adhesive property of furfuryl hyaluronic acid derivative containing ibuprofen in tendon regeneration |
| 초록 | Furfuryl hyaluronic acid derivative (F-HA) was prepared to reduce adhesion of inter-tissue after surgical operation. Hyaluronic acid has biocompatibility, wound-healing effect, and biodegradable properties. In this study, We expect that F-HA could prevent adhesion because F-HA could make physical separation by coating the surgical site. Immobilized ibuprofen as anti-inflammatory drug slowly released and reduced inflammatory response and adhesion. Structure of prepared F-HA was analyzed using 1H-NMR. Also, for medical application, biocompatibility of F-HA was evaluated by WST assay. From these results, F-HA could be developed as biocompatible anti-adhesion. Acknowledgements This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and future Planning (No. NRF-2014R1A2A1A11052623) |
| 저자 | 한가득, 김은혜, 김재원, 노승현, 손태일 |
| 소속 | 중앙대 |
| 키워드 | Anti-adhesion; Drug releasing control; ibuprofen |
