초록 |
Currently, there are a lot of researches for various compositions of interpenetrating polymeric network (IPN) or semi-IPN hydrogels with improved mechanical properties. PHEMA/chitosan and P(HEMA-co-SMA)/chitosan semi-IPN hydrogels may be expected to find use in biomedical applications such as controlled release systems and tissue engineering as scaffolds. In this study, semi-IPN hydrogels based on poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) [P(HEMA-co-SMA)], and chitosan with different molecular weights were prepared by crosslinking with ethylene glycol dimethacrylate (EGDMA) and poly(ethylene glycol) diacrylate (PEGDA) and their gelation time, water content, mechanical properties, and morphology were investigated. This research was financially supported by the Ministry of Education, Science Technology(MEST) and Korea Industrial Technology Foundation(KOTEF) through the Human Resource Training Project for Regional Innovation. |