| 초록 |
Recently, various novel inorganic/organic hybrid materials were synthesized for efficient intracellular delivery of antisense ODN, siRNA, magnetic nanoparticles, and optical imaging agents into cells. We are particularly interested in self-assembled bio-mimetic nano-biomaterials useful for therapeutic and diagnostic applications. Synthetic polymers and biomolecules have been physically and chemically hybridized to create novel functional biomaterials. In this presentation, a series of new target-specific strategies for delivering anti-sense oligonucleotides, therapeutic siRNA, and imaging agents will be mainly introduced. |
