초록 |
In vivo understanding of target molecules via molecular imaging with nanoprobe is crucial to assess indication of targeted drug and to monitor its efficacy in patients, which are the key factors in planning personalized cancer therapies. In the smart contrast agent, target contents is the cornerstone to cataloguing patient subgroups and evaluating targeted anticancer drug efficacy as well as its resistance. Further, the ultrasensitivity from high crystallized monodiverse metal oxide nanoparticle enables us to image very small sized tumor via MRI. On the other hand, in vitro measurement of target contents has a critical role to optimize personalized cancer medicine. These contents promise various nanoplatforms and nanodevices to translate precise and sensitive nanobiosensor into personalized clinical settings. |