화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터)
권호 43권 2호
발표분야 고분자가공/복합재료
제목 Nanocomposites of nano onion/molybdenum disulfide as platform of HIV -associated cancer detecting DNA biosensor
초록 The molybdenum disulfide have emerged in various fields due to optical transparency, electric bandgap, and mechanical flexibility, and thus has attracted as a next generation electronic device. Nanoonion (NO) with onion-like shell was derived from thermal annealing of nanodiamonds at 1400°C. NOs with longer molecular lattice and amorphous sp2 structure provide the capacity of electron, platform of chemical conjugation, and molecular storage that can be employed drug delivery, biosensor, and catalyst. Combining two, DNA sensor detecting HIV-associated cancer were designed by synthesizing NO/MoS2 nanocomposite. NO/MoS2 nanocomposite provide the substrate of probe DNA which can hybridize the complimentary target DNA. The addition of picogreen lead to combine the hydrogen bonds between DNA, and to amplify electrical signals by enhancing mobility. The HIV-associated cancer detecting DNA sensor was verified by amperometric singal, as well as characterization of NO/MoS2 nanocomposites.
저자 김영준1, 강은아1, 김창근1, 조용남2
소속 1중앙대, 2국립 암센터
키워드 Nanodiamond; Nanoonion; molybdenum disulfide; DNA sensor; Nano composite
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