| 초록 |
The successfully control gas release from solid film was achieved from two strategies. The increasing of diffusion path length due to the 2D-structure of graphene oxide (GO) generating the physical barrier is the first strategy. Second, the intra-hydrogen bonding from neighboring cation amine and intercalated water between GO layer act as Nitric oxide (NO) gas stabilizer. To control the releasing of NO gas, important gas in biomedical treatment, N-diazeniumdiolate (NONOate) one of NO donor source was conjugated to GO sheet and followed by fabricating to multilayers film. From using two strategies, we obtain the sustained release of NO gas with the great controllable releasing property. Furthermore, we observed the viability test and cell migration also. The result showed the non-toxic and excellent inducing the migration of HDF cells. |
