| 학회 |
한국화학공학회 |
| 학술대회 |
2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터) |
| 권호 |
22권 2호, p.2572 |
| 발표분야 |
바이오메디컬 소재 및 응용 한·일 국제 심포지엄(특별 심포지엄) |
| 제목 |
Photo-activated instant surgical tissue glue based on mussel adhesive protein and tyrosine crosslinking |
| 초록 |
Marine mussel can long-lastingly adhere to solid support in underwater environment. Interestingly, because mussel adhesive proteins (MAPs) have remarkable wet adhesion, biocompatible and biodegradable properties, they have great potential to use in body’s wet environment. Herein, we report a new light-activated, mussel protein-based bioadhesive (LAMBA) inspired by mussel adhesion and insect dityrosine crosslinking chemistry. Based on strong wet tissue adhesion, good biocompatibility and controllable crosslinking, LAMBA holds great potential as an ideal surgical tissue glue for diverse medical applications, including sutureless wound closures of skin and internal organs. |
| 저자 |
Byeong Hee Hwang1, Eun Young Jeon2, Yun Jung Yang3, Bum Jin Kim1, Bong-Hyuk Choi4, Gyu Yong Jung1, Hyung Joon Cha4
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| 소속 |
1Department of Chemical Engineering, 2POSTECH / Division of Bioengineering, 3Incheon National Univ., 4POSTECH |
| 키워드 |
수술용 접착제; 홍합접착단백질; 광가교
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| E-Mail |
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| 원문파일 |
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