| 초록 |
Nanoparticles formed by self-assembly have been extensively studied in a variety of applications due to their functional properties. In this study, a poly(2-hydroxyethyl aspartamide) (PHEA) grafted with menthyl anthranilate was successfully synthesized. Subsequently, inorganic nanoparticles were self-assembled with the grafted PHEA. This study discovered that the spike-like self-assemblies were formed when 5% hydrophobic moieties were introduced. It was confirmed that UV screening ability of the spike-like self-assemblies increases 1.8-fold compared to simple inorganic particles. Finally, nano-sized self-assemblies were applied to a cosmeceutical formulation, and then the SPF value was increased up to 52 when the assemblies were increased. Interestingly, the transparency of the formulation was about twice that of the commercial sunscreen with SPF35. These results can be utilized for innovative cosmeceutical delivery that can be used for beauty, functionality, and treatment. |
