| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 봄 (04/29 ~ 05/01, BEXCO (부산)) |
| 권호 |
19권 1호 |
| 발표분야 |
(생체재료) Smart Responsive Biomaterials |
| 제목 |
Mineralized Theranostic Nanoparticles for Cancer Treatment |
| 초록 |
The controlled deposition of biocompatible inorganic minerals on self-assembled nanostructures has broadened the chance of generating new functional nanoparticles for delivery of bioactive agents and molecular imaging. In recent years, we have focused on the biomimetic mineralization to develop the hybrid nanoparticles for intracellular drug delivery and ultrasound imaging. Herein, we describe the smart nanoparticles based on nanotemplate-based calcium phosphate (CaP) mineralization using drug-loaded polymer micelles or mesoporous silica nanoparticles as nanotemplates. In a second topic, we will focus on the gas-generating calcium carbonate (CaCO3) mineralized nanoparticles (GGMNPs) that can be used as an ultrasound (US) contrast agent. The mineralization of various templates may provide a platform technology for the generation of many high-performance nanoparticle systems for theranostic applications. |
| 저자 |
이상천 |
| 소속 |
경희대 |
| 키워드 |
mineralization; calcium carbonate; ultrasound imaging; cancer therapy
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| E-Mail |
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