| 초록 |
Titania is used in orthopaedic implants because of their biocompatibility, but the bone ingrowth properties behavior need to be improved in order to shorten the implant-tissue osseointergration time. The biocompatibility of hydroxyapatite(HAP) is closely related to its similarities with human hard tissues. Nanocomposite biomaterial consisting of hydroxyapatyite and titania (HAP/TiO2) was fabricated via electrospinning and subsequently, The tetraethyl orthosilicate(TEOS) was added in HAP/TiO2 to improve mechanical properties of nanofibers. The composite scaffolds were characterized by Scanning electron microscope(SEM), X-ray diffractometer(XRD), X-ray photoelectron spectroscopy(XPS), and Fourier-transform infrared spectrophotometer(FT-IR) techniques and cell culture experiments. The potential for use of this nanocomposite as bone scaffolds was assessed by osteoblastic cell (MC3T3-E1) in terms of attachment, proliferation and differentiation. |
