| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Direct comparison of cell adhesion and alignment on RGD peptide and Graphene oxide micropattern-arrays |
| 초록 |
Graphene is a two-dimensional (2D) carbon nanomaterial, which has garnered much attention owing to its excellent electrical, chemical, optical, and mechanical properties. In particular, graphene oxide (GO) with the high ratio of surface area and numerous functional groups has made it one of the most interesting materials as a biocompatible interface for cell adhesion and growth. Here, we developed a simple strategy to produce selectively micropatterned surfaces consisting of layered RGD and GO stripes by the combination of a self-assembly process and conventional lithography. By the cell culture of fibroblasts (L929), the unique features of the alternatively patterned substratum could give us chance to study critical cell adhesion onto the distinctive surface area of GO or RGD through the direct comparison. As a result, we observed that the micropatterned GO thin films showed the superior focal point of cell attachment with higher cell adhesion compared to the RGD regions. |
| 저자 |
신민찬, 송수진, 박로운, 채선영, 한동욱, 홍석원
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| 소속 |
부산대 |
| 키워드 |
Graphene oxide; RGD peptide; micropattern; cell adhesion
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| E-Mail |
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