| 초록 |
Polymeric microcapsules with controlled morphology and functional properties have attracted considerable interest recently due to their potential utilization as encapsulants for the controlled release of drugs, dyes, enzymes, cosmetics, pesticides, food additives etc. Microcapsules fabricated with biopolymers likewise possess promising applications in the encapsulation of transplanted cells by providing a feasible microenvironment. In this presentation, we report the synthesis of various synthetic polymer-block-polypeptide copolymers by combining ATRP and α-aminoacid-N-carboxyanhydrides-ROP, intermediated by a similar nickel amido-amidate moiety. In addition we describe a straightforward microfluidic method for producing reversibly swellable microcapsules with high porosity using amphiphilic synthetic polymer-block-polypeptide copolymers. The capability of these capsules to encapsulate quantum dots and stimuli assisted release is to be demonstrated. |
