화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 Bio-active, functional macromolecules and nanomaterials
제목 Development of Stimuli-responsive Polypeptides for Biomedicine, Tissue Engineering and Drug Delivery
초록 Stimuli-responsive polypeptides for biomedicine, tissue engineering and drug delivery have been recently explored.We have been developing thermally-responsive elastin-like polypeptides (ELPs), artificial repetitive polypeptides.We reported a series of biotechnological and biomedical applications of ELPs, and their fusions with functional proteins: (1) non-chromatographic protein purification; (2) control of biophysical property of ELPs and ELP fusions; and (3) temperature-triggered, self-assembling ELP nanostructures and hydrogels for drug delivery and tissue engineering.This study opens a new avenue for developing smart polypeptide-based materials.
저자 임동우
소속 한양대
키워드 Biomaterials; Polypeptides; Biomedicine; Tissue Engineering; Regenerative Medicine; Drug Delivery
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