화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2008년 가을 (10/09 ~ 10/10, 일산킨텍스)
권호 33권 2호
발표분야 의료용 고분자 부문위원회
제목 Preparation and Application of Thermosensitive Nanoparticle using Low Molecular Weight Water-Soluble Chitosan-g-Poly(N-isopropylacrylamide)
초록 The carboxyl terminated poly(N-isopropylacrylamide)(PNIPAAm) was synthesized by radical chain-transfer Polymerization. The PNIPAAm was successfully synthesized by radical chaintransfer polymerization using 3-mercaptopropionic acid(3-MPA) as chain trans fer agent with AIBN as a radical initiator. We synthesized a PNIPAAm grafted Low molecular weight water-soluble chitosan(chitoPAAm) to prepare a retinoic acid(RA) encapsulated copolymer. The RA-encapsulated chitoPAAm copolymer had a particle size of 150-200nm and a spherical shape when observed by transmission electronmicroscopy.
저자 김동곤1, 남정표1, 허선행1, 정현1, 정영일1, 장미경1, 권중근2, 나재운1
소속 1순천대, 2조선이공대
키워드 Low molecular weight water soluble chitosan; Poly(N-isopropylacrylamide; Nanoparticle
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