| 학회 | 한국화학공학회 |
| 학술대회 | 2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
| 권호 | 20권 2호, p.2479 |
| 발표분야 | 신진연구자 심포지엄 |
| 제목 | Enzyme-based biocatalysts for CO2 sequestration |
| 초록 | Carbonic anhydrase (CA) is an enzyme that catalyzes reversible hydration of CO2. It has been recently suggested that this remarkably fast enzyme can be used for sequestration of CO2, making this a promising alternative for chemical CO2 mitigation. For its practical application, we developed efficient and economic biocatalysts with high stability, mainly based on a recombinant CA originated from Neisseria gonorrhoeae (ngCA). First, we engineered ngCA in the periplasm of E. coli to promote the economical use of enzymes, thereby creating a bacterial whole-cell catalyst. Next, we developed and characterized bioinspired silica nanoparticle with recombinant ngCA autoencapsulated by the silica-condensing R5 peptide fused to the ngCA. Finally, we found and characterized thermophilic α-CAs originated from Persephonella marina and Thermovibrio ammonificans, demonstrating their remarkable thermostabilities. |
| 저자 | 조병훈 |
| 소속 | 포항공과대 |
| 키워드 | Carbonic Anhydrase; Carbon Capture; Biocatalyst |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
