화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU))
권호 22권 2호
발표분야 생체재료_포스터
제목 Improvement of Bioactivity of Chitosan-Collagen Complex Scaffold by Incorporated Drug
초록 3D porous scaffolds are widely used in tissue engineering to support and regenerate damaged tissues. The pre-requisites for the scaffolds include biocompatibility, biodegradability, porosity, and hydrophilicity to promote cell adhesion, proliferation, and differentiation. In this investigation, we prepared chitosan and collagen complex scaffolds. The effects of combination with drug-containing calcium phosphate on the physical and biological properties of the scaffolds, including morphology, porosity, and elemental composition, were evaluated using various analytical techniques, including SEM, EDS, FT-IR, and cell assays. It was observed that the bioactivity of the scaffold was considerably affected by the combination of calcium phosphate particles and furthered by drug-incorporation.
저자 김정헌, 김민정, 박은현, 송민주, 이민선, 이병학, 임예람, 이우걸
소속 단국대
키워드 Keywords: Chitosan; collagen; porous scaffold; CaP particle; drug
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