초록 |
3D porous scaffolds are widely used in tissue engineering to support and regenerate damaged tissues. The pre-requisites for the scaffolds include biocompatibility, biodegradability, porosity, and hydrophilicity to promote cell adhesion, proliferation, and differentiation. In this investigation, we prepared chitosan and collagen complex scaffolds. The effects of combination with drug-containing calcium phosphate on the physical and biological properties of the scaffolds, including morphology, porosity, and elemental composition, were evaluated using various analytical techniques, including SEM, EDS, FT-IR, and cell assays. It was observed that the bioactivity of the scaffold was considerably affected by the combination of calcium phosphate particles and furthered by drug-incorporation. |