화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2015년 가을 (10/21 ~ 10/23, 일산 KINTEX)
권호 21권 2호, p.1763
발표분야 생물화공
제목 CeO2 Nanostructure based Electrochemical Biosensor for Hydrogen Peroxide Detection
초록 A facile and sensitive amperometric detection of H2O2 was developed based on direct electrochemistry of myoglobin immobilized on a porous CeO2 nanostructured film which was electrodeposited on an ITO. The ITO/CeO2 Substrate Surface, characterized by scanning electron microscopy, revealed a large specific surface area with a unique nanostructure of CeO2 on the ITO. Electrochemical behavior of adsorbed Mb on the fabricated substrate was investigated by cyclic voltammetry and differential pulse voltammetry techniques, showing a considerable electrocatalytic performance without the presence of any electron mediator. The proposed protein-based biosensor showed linear response up to a concentration of 3 mM having a detection limit of 0.6 µM and a response time of approximately 8 s, compared to those of other modified electrodes. Therefore results proved that, well-dispersed and high surface area of the modified electrode as well as direct electron transfer of protein could be a promising method for electrochemical biosensors. Acknowledgments: This work was supported by Samsung Research Funding Center of Samsung Electronics under Project Number SRFC-MA1401-04.
저자 최정우1, 민준홍2, 이 택1, 아자이 쿠마르 야가티1, 모하마드니아이 모센1
소속 1서강대, 2중앙대
키워드 myoglobin; cyclic voltammetry; differential pulse voltammetry; electrochemical biosensors
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