| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Detection of Antigen molecules using Antibody-anchored liquid crystal microdroplets |
| 초록 |
Liquid crystal(LC) microdroplets have attracted considerable attention not only as chemical targeting but also as biological agents. The change in configuration was observed from radial to bipolar or vice versa due to external stimuli. 4-Cyano-4´-pentylbiphenyl(5CB, nematic liquid crystal) microdroplets were prepared by using O/W emulsion system. Amphiphilic diblock copolymer of poly (Styrene-b-acrylic acid) (PS-b-PA) was used as a surfactant to prepare the emulsion. The hydrophobic styrene block is miscible with the hydrophobic 5CB and incorporates in the micelle core. The hydrophilic PA block is in the outer shell. We introduced anti-IgG(antibody) on the surface of the LC microdroplets as a hosting platform for protein immunoassays. Also we studied the effect of IgG(antigen) concentration on sensing ability of LC droplets and further selective detection of the LC droplets in mixed protein solution. |
| 저자 |
이규배, 권기완, 강인규
|
| 소속 |
경북대 |
| 키워드 |
Amphiphilic diblock copolymer; liquid crystal microdroplet; immunoassay
|
| E-Mail |
|
