| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
학생우수논문발표(석사과정) |
| 제목 |
Release properties of naproxen loaded biodegradable polymers based multi-layer biomaterials |
| 초록 |
In this work, multi-layer biomaterials were prepared using allbanggae starch (ABG), sodium alginate (SA), polyvinyl alcohol (PVA), naproxen (NP) as the target drug, and glycerol (GL) as a plasticizer. The first and third-layer were prepared SA based biomaterials, the second-layer was prepared NP loaded ABG based biomaterials. The prepared multi-layer biomaterials were characterized by FT-IR and FE-SEM. Their physical properties were also evaluated. The NP release properties of multi-layer biomaterials were performed using standard buffer solutions and artificial skin at 36.5℃. Results of NP release properties indicated that NP release rate of multi-layer biomaterials was slower than the single-layer biomaterials. In case of NP release using artificial skin, NP release rate of multi-layer biomaterials was about 5 times slower than the single-layer biomaterials. From the results, we suggest that SA_ABG based multi-layer biomaterials can be sustained release of NP. |
| 저자 |
조은비, 김한성, 김경중, 정헌호, 윤순도, 변헌수
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| 소속 |
전남대 |
| 키워드 |
Naproxen; Allbanggae starch; Multi-layer biomaterial; Release properties
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| E-Mail |
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