| 초록 |
In this study, we introduced a solar cell-based patch that can be applied to skin wound sites to control cellular microenvironment for promoting wound healing by generating electrical stimulation (ES). Our experiment results showed that exogenous ES could enhance cell migration, expression of extracellular matrix proteins, myoblast differentiation, host-inductive cell proliferation, cytokine secretion, and protein synthesis which is critical for wound healing process. Unlike the current treatments for wound healing that engage passive healing processes and often are unsuccessful, our wearable solar cell-based patch can stimulate regenerative activities of endogenous cells and actively contribute to the wound healing processes. |
