| 학회 | 한국고분자학회 |
| 학술대회 | 2005년 봄 (04/14 ~ 04/15, 전경련회관) |
| 권호 | 30권 1호, p.410 |
| 발표분야 | 기능성 고분자 |
| 제목 | Preparation of MMA-based Amphiphilic Nonfouling Surface |
| 초록 | In the presentation we demonstrate a preparation method of amphiphilic MMA surfaces with a short nonfouling oligoethylene glycol side-chain that enables long-term, cell repellant surfaces. The MMA based nonfouling polymer was synthesized by free radical polymerization of methylmethacrylate (MMA), poly(ethylene glycol) methacrylate (referred to herein as hydroxy-poly(oxyethylene) methacrylate, HPOEM) and poly(ethylene glycol) methyl ether methacrylate (referred to herein as poly(oxyethylene) methacrylate). The number average molecular weight (MW) of the comb polymer (Mn) was ~30,000 Da with a polydispersity of ~2.3, as measured by gel permeation chromatography using PS calibration standards. The composition of the terpolymer was characterized by 1H NMR in CDCl3. The nonfouling property of the polymer spin-cast on a variety of substrates was confirmed with the adsorption experiment of cell-lysate and protein solutions. We also demonstrate that the MMA-based nonfouling surface has the potential to become a powerful tool to control the seeding of cells. Fig. 1. Chemical structure of amphiphilic nonfouling polymer |
| 저자 | 김윤아1, 현진호1, 신병철2 |
| 소속 | 1서울대, 2한국화학(연) |
| 키워드 | MMA; HPOEM; POEM; radical polymerization; nonfouling; cell |
