화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터)
권호 36권 1호
발표분야 대학원생 구두발표
제목 Water-soluble polymer-based fluorescence detection of biopolymers through the interaction between anionic Poly(phenylene-vinylene)s and cationic acceptors
초록 Polyelectrolytes are water-soluble polymers containing multiple pendant charges. Polyelectrolytes are sensitive to minor perturbations (high sensitivity), due to amplication by the collective response (polymeric nature), which offer advantages when compared with small molecule counterparts. The amplified fluorescence sensitivity of biological detection is the key feature used in biosensors. Herein, the use of anionic water-soluble conjugated polymers (CPs) for sensing of biopolymers by virtue of a cationic quencher was studied. The fluorescence of MPS-PPV was quenched by PABH through electrostatic attraction, the quenched fluorescence of MPS-PPV was recovered by biopolymers which was attributed to perturbation of the interaction between MPS-PPV and PABH as PABH is a good biopolymer binder, accordingly, the biopolymers was detected.
저자 왕정, 하창식
소속 부산대
키워드 Polyelectrolytes; cationic quencher; biopolymers; fluorescence; binding sites; sensitivity
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