| 초록 |
We have developed magnetic nanoparticles (MPs) with small hydrodynamic radius, containing various functional groups that readily compatible for conjugation to bio-molecules. The main advantage of making smallest MPs as possible is that we expect to see the enhancement in many properties including increase of diffusion rate and decrease of steric hindrance to bio-molecule conjugation when compared to the larger MPs. To achieve this goal, we’d like to design new biocompatible lidands, modify the surface of nanomaterials using newly designed molecules by ligand exchange method, and finally test the cell viability of those new materials by incubating in the cell. |
