| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
고분자합성 |
| 제목 |
Synthesis and Characterization of Well-Defined Brush Polymers Bearing Sulfobetaine Moieties |
| 초록 |
A series of well-defined brush polymers, poly(oxy(11-(3-sulfonylpropyltrimethyl-glycinyl)undecylesterthiomethyl) ethylene-co-oxy(n-dodecylthio-methyl)ethylene)s (PECH-DMAPSm, where m is the mol% of the DMAPS [sulfobetaine] end group) were synthesized. The thermal properties and phase transitions of these polymers were investigated. The polymers were thermally stable up to 185 oC and were found to form favorably into multibilayer structures, always providing hydrophilic, zwitterionic sulfobetaine end groups at the film surface. Because of the presence of these sulfobetaine groups at the surface, the polymer films promoted HEp-2 cell adhesion and revealed biocompatibility in mice but significantly suppressed protein adsorption. These results collectively indicate that the sulfobetaine-containing brush polymers are suitable for use in biomedical applications, including medical devices and biosensors that require biocompatibility. |
| 저자 |
권경호1, 권원상1, 노예철1, 안병철1, 정정운1, 김경태1, 김미희1, 고용기1, 정성민1, 송성진1, 김희수2, 이문호1, 김종현1, 이진석1, 위동우1, 김영용1
|
| 소속 |
1포항공과대, 2동국대 |
| 키워드 |
brush polymer; sulfobetaine; self-assembly; water sorption; water contact angle; protein adsorption; celladhesion; biocompatibility
|
| E-Mail |
|
