| 초록 |
Hexanoic acid is used as a food additives and perfume, and by chemical catalyst, can be converted to hexanol that would be utilized as a transport fuel. In this study, for the enhancement of hexanoic acid production the co-culture bioprocess was developed with Clostridium tyrobutyricum producing butyric acid and Megasphaera hexanoica producing hexanoic acid from butyric acid. Two bacterial strains were cultivated in two hollow-fiber membrane bioreactors (HfMBR), respectively. Each fermentation broth was filtrated through hollow-fiber membrane modules and the filtrated broth was interchanged on another one. Using optimized conditions, hexanoic acid concentration increased to about 9g/L in both reactors. From the extractive fermentation with oleyl alcohol mixed with alamine336, hexanoic acid was produced up to 100g/L. It indicates that the co-culture in the HfMBRs using Clostridium tyrobutyricum and Megasphaera hexanoica can be feasible process for commercial production of hexanoic acid. |
