| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 가을 (10/06 ~ 10/08, 제주 ICC) |
| 권호 |
39권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Hydrophobized SF nanofibrous mat as a GBR membrane |
| 초록 |
Guided bone regeneration (GBR) method is a well-established therapy to repair mandible and alveolar bone defects infected by periodontal diseases. Silk fibroin is widely used for tissue engineering scaffold because of their biocompatibility, biodegradability and non-toxicity. We have been used electrospinning technique which is simply used to fabricate nanofibrous mats. Conformational change of SF was induced by water vapor treatment from random coil to ß-sheet structures determined by ATR-FTIR. After CF4 gas plasma treatment, the surface property of SF nanofibrous mats was dramatically changed to hydrophobic determined by water contact angle measurement. Fibroblasts' viability on CF4 gas plasma treated and untreated SF nanofibrous mats was determined by MTT assay. The tissue barrier effect of SF nanofibrous mats was confirmed using New Zealand white rabbits. SF nanofibrous mats with extremely hydrophobic surface can be used as guided bone regeneration (GBR) membranes. |
| 저자 |
이민영1, 이재백2, 방수미2, 박원호3, 조동환2, 권오형2
|
| 소속 |
1국립금오공과대, 2금오공과대, 3충남대 |
| 키워드 |
silk fibroin; nanofiber; electrospinning; GBR membrane
|
| E-Mail |
|
