| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 | 27권 2호, p.319 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Thermo-sensitive sol-gel transition behavior of star-shaped PEG-PLGA-PEG aqueous solution |
| 초록 | Thermo-sensitive polymers as drug carriers have attracted considerable attention. Hydrophobic blocks of several amphiphilic block copolymers form hydrophobic association as temperature changes, which induces temperature sensitive phase transition. In this study, biodegradable star-shaped poly(ethylene glycol-b-D,L lactide-co-glycolide-b-ethylene glycol) synthesized. 1H NMR, 13C NMR and GPC are uesed to characterize this polymer. Using UV-Vis spectroscopy and dynamic light scattering, critical micellization concentration and micelle size were determined. And thermo-sensitive sol-gel transition behavior of the block copolymer was investigated by tube tilting method. |
| 저자 | 한보령1, 박상엽2, 김성철 |
| 소속 | 1한국과학기술원, 2기능성 고분자 신소재 연구센터 |
| 키워드 | |
